Regenerative choices. Proven by science. And you.

Introducing Symbios, a full range of quality allograft, xenograft and alloplast bone graft and membrane products designed to promote excellent long-term bone growth and stability. This comprehensive offering consistently delivers predictable clinical efficacy, biocompatibility, ease and use you can rely on.

Because bone quality is important, we source our allograft products from the Musculoskeletal Transplant Foundation (MTF), the world’s largest AATB (American Association of Tissue Banks) accredited tissue bank. This includes PerioDerm® Acellular Dermis allograft, which replaces damaged or inadequate tissue for the repair, reinforcement or supplemental support of soft tissue defects. 

DENTSPLY Implants offers a full line of dental membranes including synthetic, bovine resorbable and an allograft acellular dermal matrix. The two key brands are PerioDerm® and OsteoShield®. 



Symbios® PerioDerm® Acellular Dermis

PerioDerm® Acellular Dermis is minimally processed to remove epidermal and dermal cells while preserving the extra-cellular matrix. The removal of viable cells and antigens during the decellularization process minimizes the risk of rejection and inflammation at the surgical site. The remaining matrix serves as a framework for cellular infiltration and vascularization. PerioDerm Acellular Dermis has been shown to support the migration of host cells from wound margins and surrounding tissues. Each PerioDerm graft is aseptically processed and packaged in Class 10 (certified) clean rooms at MTF’s state-of-the-art dermis processing facility.

  • Rehydrates quickly (3-5 minutes)
  • Freeze-dried (no refrigeration required)
  • Over 90% thickness consistency for uniform revascularization
  • No cross-linking
  • 3 year shelf life



Symbios® OsteoShield® Collagen Resorbable Membrane





Symbios® OsteoShield® PTFE Non-Resorbable Membrane

  • Non-Resorbable, yet easily removable, d-PTFE membrane for use with extraction site grafting, large bony defects and where primary closure is not possible or not desired
  • Primary closure is not required – this membrane is virtually impervious to bacteria, resulting in minimal risk of bacterial invasion
  • By avoiding releasing incisions and primary closure, soft tissue architecture is maintained, keratinized mucosa is preserved and minimal flap reflection or dissection if required
  • The exposed membrane may be easily removed non-surgically
  • Medical grade d-PTFE is biocompatible and non-reactive
  • Micro-machined surface texture facilitates cell adhesion, enhances membrane stability, reduces flap retraction and increases pull-out strength


Symbios® OsteoShield® Titanium-Reinforced Non-Resorbable Membrane

  • This titanium-reinforced membrane for use with large defects, two- or three-walled defects or where space-making is required
  • Self-supporting titanium-reinforcement which helps create additional space, especially in defects with deficient bony architecture
  • Titanium-reinforcement prevents folding or wrinkling allowing for easy placement
  • Grade 1 titanium has little to no memory making shaping of the membrane very easy  

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Correcting Severe Class II Gingival Recession Using Symbios® PerioDerm®

The Use of PerioDerm™ for Root Coverage and Correction of Insufficient Attached Gingiva